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What is the primary function of corneocytes in the epidermis?

  1. To act as a barrier against pathogens

  2. To provide cellular glue holding cells together

  3. To facilitate the absorption of nutrients

  4. To produce melanin for skin pigmentation

The correct answer is: To provide cellular glue holding cells together

The primary function of corneocytes in the epidermis is to provide structural integrity to the skin. These are the dead skin cells that fill the outermost layer of the epidermis, known as the stratum corneum. Corneocytes are tightly packed together and play a vital role in forming a protective barrier that helps to prevent water loss and shield the underlying layers of the skin from external threats. The cellular composition of corneocytes, enriched with keratin, enables them to fulfill their role as a formidable barrier, resisting mechanical stresses and microbial invasion. This function is crucial in maintaining skin hydration and overall health. While corneocytes do contribute to some aspects of adhesion between skin layers, their primary significance lies in their role as a protective barrier rather than only providing cellular glue.