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What is the primary function of histamines in allergic reactions?

  1. Increase pain sensation

  2. Cause inflammation

  3. Regulate blood pressure

  4. Enhance skin elasticity

The correct answer is: Cause inflammation

The primary function of histamines in allergic reactions is to cause inflammation. When the immune system encounters an allergen, histamines are released from mast cells. This release is part of the body's defense mechanism aimed at expelling irritants from the body. The histamines increase the permeability of blood vessels, leading to fluid leakage into surrounding tissues. This results in the redness, swelling, and warmth characteristic of inflammation, which is a common response to allergens. The other options represent functions that do not accurately describe the role of histamines during an allergic reaction. While histamines can indirectly influence pain sensation and have some involvement in blood pressure regulation, their primary and most notable impact lies in the inflammatory response associated with allergic reactions. Histamines do not enhance skin elasticity, as that function is related to other biological factors like collagen and elastin.