Utah Esthetics Written State Practice Exam

Which structures act as connectors of upper epidermal tissue?

1. Desmosomes

2. Gap junctions

3. Tight junctions

4. Hemidesmosomes

The correct answer is: Desmosomes

Desmosomes are specialized structures that function as connectors of upper epidermal tissue by anchoring adjacent cells together. They are particularly important in areas of high mechanical stress, such as the skin, where they provide structural integrity and stability to the tissue. By linking the cytoskeletons of neighboring cells, desmosomes help maintain the epidermal barrier and prevent the separation of cells under tension, which is crucial for the protective functions of the skin. The other structures listed have different roles: gap junctions facilitate intercellular communication through channels that allow ions and small molecules to pass directly between cells, while tight junctions create a barrier to prevent leakage between cells in epithelial tissues. Hemidesmosomes, on the other hand, anchor epithelial cells to the underlying basement membrane rather than connecting them to adjacent cells. Understanding these distinct functions helps clarify why desmosomes are specifically important for connecting upper epidermal tissue.